Main Street Inn
404 S. Main St., Galena, IL 61036
Vacation Rentals
Located on Galena's historic downtown Main Street, the Main Street Inn is a cozy, inviting place to relax that is listed on the National Register of Historic Places (circa 1850).
Main Street Inn offers 6 luxurious and spacious rooms located on the 2nd floor that will meet the needs of romantic adventures, friend getaways, or anything in between. Walk out the front door to take a stroll up Main Street and browse through Galena's unique stores and boutiques, enjoy dining at one of Galena's fine restaurants, or stop by one of our wine shops. Or stay in and simply enjoy the comforts of your room.
Whatever your reason for coming to Galena, the Main Street Inn is here for you!
What's happening nearby...

Galena Sky Trail Races
Chestnut Mountain Resort • May 17 @ 8AM
Looped course that brings you back to a jammin' party every time. DJ, music, and fun after party! There will be prizes for the after party.…
Read more about Galena Sky Trail Races
Live @ The Plaza
Green Street Plaza • May 29 @ 5PM
Visit the Plaza to enjoy live music, good food and immerse in the community!
Read more about Live @ The Plaza
2025 Galena Pride Picnic
Grant Park • Jun 14 @ 12noon
Celebrate diversity, love, and unity at Galena's annual Pride Picnic, organized by the Galena Public Library!
Read more about 2025 Galena Pride PicnicYou might also be interested...

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