Main Street Inn
404 S. Main St., Galena, IL 61036
Vacation Rentals
Located on Galena's historic downtown Main Street, the Main Street Inn is a cozy, inviting place to relax that is listed on the National Register of Historic Places (circa 1850).
Main Street Inn offers 6 luxurious and spacious rooms located on the 2nd floor that will meet the needs of romantic adventures, friend getaways, or anything in between. Walk out the front door to take a stroll up Main Street and browse through Galena's unique stores and boutiques, enjoy dining at one of Galena's fine restaurants, or stop by one of our wine shops. Or stay in and simply enjoy the comforts of your room.
Whatever your reason for coming to Galena, the Main Street Inn is here for you!
What's happening nearby...

Haunted Galena Conference
DeSoto House Hotel • Apr 04 – Apr 06 @ 4PM
Embrace the Darkness with Haunted Galena Tour Company at the haunted DeSoto House Hotel!
Read more about Haunted Galena Conference
Kiwanis River Trail Run
Galena River Trail • Apr 19 @ 10AM
The Kiwanis Club of Galena invites you to sign up for their Annual Run with proceeds benefitting local organizations with supporting children and improving the quality…
Read more about Kiwanis River Trail Run
Julien Dubuque International Film Fest Screenings in Galena
Galena Center for the Arts, DeSoto House Hotel • Apr 21 – Apr 22 @ 10AM
The Julien Dubuque International Film Festival (JDIFF) begins with the first 2 days in Galena in the Desoto House Hotel and the Galena Center for the Arts
Read more about Julien Dubuque International Film Fest Screenings in GalenaYou might also be interested...

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